Annual report pursuant to Section 13 and 15(d)

Liquidity and Plan of Operations (Details Narrative)

v3.22.0.1
Liquidity and Plan of Operations (Details Narrative) - USD ($)
 1 Months Ended 12 Months Ended
Jan. 14, 2020
Jan. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Accumulated deficit     $ 131,634,208 $ 107,507,193  
Net loss     23,300,000 22,400,000  
Gross proceeds from public offering of common stock $ 50,000,000.0   5,580,471 46,704,210  
Net proceeds from public offering of common stock 46,700,000        
Cash and cash equivalents     21,029,806 12,432,481 $ 22,170,000
Marketable securities     28,592,049 $ 46,246,573  
Restricted cash     $ 300,000    
Underwritten Public Offering [Member]          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Gross proceeds from public offering of common stock 50,000,000.0        
Net proceeds from public offering of common stock $ 46,700,000        
At The Market Sales Agreement [Member]          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Proceeds from public offering, gross   $ 5,800,000      
Gross proceeds from public offering of common stock   $ 5,600,000      
Common Stock [Member]          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Number of underwritten public offering of common stock 32,260,000   3,023,147 32,260,000  
Common Stock [Member] | Underwritten Public Offering [Member]          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Number of underwritten public offering of common stock 32,600,000